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Probiotic Supreme DF™ is a higher dose, dairy-free alternative to our Probiotic Synergy™, delivering 15 billion organisms per dose in a caplet form, and using the same advanced patented delivery system to ensure the highest number of live organisms to the intestinal tract. As probiotics are meant to be released over an extended time frame of 10 to 12 hours, effective dosing is delivered only once per day. This also ensures delivery throughout the entire intestinal tract.